Anti-Mouse MAdCAM-1 Recombinant Antibody|抗小鼠MAdCAM-1重组抗体(靶标：小鼠黏膜地址素细胞黏附分子1)
- 货号：RB9TMC589013
- 价格：面议
- 点击：324
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rat |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG2a, kappa |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | IP, WP, Block, FCM, IHC |
| 种属反应性 | Mus musculus (Mouse) |
| 靶标 | MAdCAM-1, Madcam1, Mucosal addressin cell adhesion molecule 1, mMAdCAM-1 |
| 储存缓冲液 | 0.01M PBS pH 7.4 |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 重构方法 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 登录号 | Q61826 |
| 背景信息 | Mucosal addressin cell adhesion molecule 1 (MAdCAM-1) is a ~43 kDa protein. Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both the integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Both isoform 1 and isoform 2 can adhere to integrin alpha-4/beta-7. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding. |
| 备注 | For research use only |
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