| 形态 | Liquid |
|---|---|
| 宿主种属 | Humanized |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG1-kappa |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 1 mg/ml |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 靶标 | T-cell growth factor P40, Cytokine P40, IL9, Interleukin-9, IL-9 |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 表达系统 | Mammalian Cells |
| 登录号 | P15248 |
| 背景信息 | Enokizumab (MEDI-528) is a monoclonal antibody targeting to interleukin (IL)-9. IL-9 regulates the development of airway inflammation, mucus production, airway hyperresponsiveness, and airway fibrosis largely by increasing mast cell numbers and activity in the airways. • IL-9 secreted by leukemia stem cells induces Th1-skewed CD4+ T cells, which promote their expansion., PMID:38941612 • Positive feedback loop PU.1-IL9 in Th9 promotes rheumatoid arthritis development., PMID:39164066 • The Role of Interleukin-9 in Cancer., PMID:31016637 • IL-9, a local growth factor for synovial T cells in inflammatory arthritis., PMID:26751012 • Locus of (IL-9) control: IL9 epigenetic regulation in cellular function and human disease., PMID:38825637 • Interleukin-9 and mast cells., PMID:23034251 • IL-9 sensitizes human TH2 cells to proinflammatory IL-18 signals in atopic dermatitis., PMID:39521283 • IL-9 and IL-9-producing cells in tumor immunity., PMID:32228589 • Interleukin-9 and T helper type 9 cells in rheumatic diseases., PMID:27159882 • IL-9-producing T cells: potential players in allergy and cancer., PMID:32788707 |
| 别名 | 7F3com-2H2, MEDI-528, 909875-08-7 |
| 种属 | Human |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
| 产品名称 | 点击数 |
|---|---|
| 炔诺酮单抗 | 5915 |
| 磺胺氯吡嗪单抗 | 5909 |
| 呋喃苯烯酸钠单抗 | 5700 |
| 呋喃它酮代谢物(2-NPAMOZ)单抗 | 5705 |
| 呋喃西林代谢物(2-NPSEM)单抗 | 5525 |
| 磺胺喹恶啉单抗 | 5801 |
| 苯丙酸诺龙单抗 | 5704 |
| 司帕沙星单抗 | 5569 |
| 妥布霉素单抗 | 5717 |
| 甲氧氯普胺单抗 | 5553 |
| 莫能菌素单抗 | 5713 |
| 多粘菌素B(粘菌素)单抗 | 6042 |
| 磺胺类单抗 | 5945 |
| 托灭酸(托芬那酸)单抗 | 5579 |
| 卡洛芬单抗 | 5529 |
| 喹乙醇代谢物MQCA单抗 | 5699 |
| 氟尼辛单抗 | 5700 |
| 磺胺二甲嘧啶(SM2)单抗 | 5440 |
| 诺龙(19-去甲睾酮)单抗 | 5539 |
| 阿苯达唑-2-氨基砜单抗 | 5472 |