| 形态 | Liquid |
|---|---|
| 宿主种属 | Humanized |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG1-kappa |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 1 mg/ml |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 靶标 | T-cell growth factor P40, Cytokine P40, IL9, Interleukin-9, IL-9 |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 表达系统 | Mammalian Cells |
| 登录号 | P15248 |
| 背景信息 | Enokizumab (MEDI-528) is a monoclonal antibody targeting to interleukin (IL)-9. IL-9 regulates the development of airway inflammation, mucus production, airway hyperresponsiveness, and airway fibrosis largely by increasing mast cell numbers and activity in the airways. • IL-9 secreted by leukemia stem cells induces Th1-skewed CD4+ T cells, which promote their expansion., PMID:38941612 • Positive feedback loop PU.1-IL9 in Th9 promotes rheumatoid arthritis development., PMID:39164066 • The Role of Interleukin-9 in Cancer., PMID:31016637 • IL-9, a local growth factor for synovial T cells in inflammatory arthritis., PMID:26751012 • Locus of (IL-9) control: IL9 epigenetic regulation in cellular function and human disease., PMID:38825637 • Interleukin-9 and mast cells., PMID:23034251 • IL-9 sensitizes human TH2 cells to proinflammatory IL-18 signals in atopic dermatitis., PMID:39521283 • IL-9 and IL-9-producing cells in tumor immunity., PMID:32228589 • Interleukin-9 and T helper type 9 cells in rheumatic diseases., PMID:27159882 • IL-9-producing T cells: potential players in allergy and cancer., PMID:32788707 |
| 别名 | 7F3com-2H2, MEDI-528, 909875-08-7 |
| 种属 | Human |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
| 产品名称 | 点击数 |
|---|---|
| 阿苯达唑砜单抗 | 5779 |
| 金刚烷胺单抗 | 5852 |
| 卡那霉素单抗 | 5943 |
| 黄曲霉毒素M1(AFM1)单抗 | 5957 |
| 群勃龙(孕三烯酮)(去甲雄三烯醇酮)单抗 | 6367 |
| 帕托珠利(妥曲珠利砜)单抗 | 5802 |
| 泰乐菌素单抗 | 5914 |
| 替米考星单抗 | 5965 |
| 新霉素单抗 | 5994 |
| 安普霉素单抗 | 5951 |
| 三聚氰胺(MEL)单抗 | 5851 |
| 双氟沙星单抗 | 5810 |
| 西地那非单抗 | 5908 |
| 阿苯达唑单抗 | 5707 |
| 醋酸甲羟孕酮(醋酸甲孕酮)单抗 | 5877 |
| 氟苯尼考单抗 | 5931 |
| 诺龙单抗 | 6022 |
| 达氟沙星单抗 | 6120 |
| 培氟沙星单抗 | 5957 |
| 庆大霉素单抗 | 6088 |