Anti-Human CD14 Reference Antibody|抗人CD14参考抗体(靶标：人CD14)
- 货号：RB9THY038016
- 价格：面议
- 点击：652
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Chimeric |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG4-kappa |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 1 mg/ml |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 靶标 | Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14 |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 表达系统 | Mammalian Cells |
| 登录号 | P08571 |
| 背景信息 | Atibuclimab, is a chimeric monoclonal antibody directed against CD14 and is composed of murine variable and human IgG4 Fc regions. Atibuclimab can be used for the research of amyotrophic lateral sclerosis. Atibuclimab attenuates LPS-induced symptoms and strongly inhibits LPS-induced proinflammatory cytokine release, while only delaying the release of the anti-inflammatory cytokines soluble TNF receptor type I and IL-1 receptor antagonist. • Single-cell analysis of human skin identifies CD14+ type 3 dendritic cells co-producing IL1B and IL23A in psoriasis., PMID:34279540 • BCG Vaccination in Humans Elicits Trained Immunity via the Hematopoietic Progenitor Compartment., PMID:32544459 • Tissue CD14+CD8+ T cells reprogrammed by myeloid cells and modulated by LPS., PMID:36697826 • Presepsin for the Diagnosis of Neonatal Early-Onset Sepsis: A Systematic Review and Meta-analysis., PMID:35639395 • Monocyte isolation techniques significantly impact the phenotype of both isolated monocytes and derived macrophages in vitro., PMID:31573680 • Differential IRF8 Transcription Factor Requirement Defines Two Pathways of Dendritic Cell Development in Humans., PMID:32735845 • Mouse and human CD14 (myeloid cell-specific leucine-rich glycoprotein) primary structure deduced from cDNA clones., PMID:2472171 • Causal relationship between immune cells and epilepsy mediated by metabolites analyzed through Mendelian randomization., PMID:39179617 • Three distinct tolerogenic CD14+ myeloid cell types to actively manage autoimmune disease: Opportunities and challenges., PMID:33901801 • The co-location of CD14+APOE+ cells and MMP7+ tumour cells contributed to worse immunotherapy response in non-small cell lung cancer., PMID:39187937 |
| 别名 | 28C5, termed IC14, 2417175-94-9 |
| 种属 | Human |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
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