当前位置:首页>产品中心>单抗/多抗>Anti-Human ICAM-1/CD54 Reference Antibody|抗人ICAM-1/CD54参考抗体(靶标:人CD54(ICAM-1))

Anti-Human ICAM-1/CD54 Reference Antibody|抗人ICAM-1/CD54参考抗体(靶标:人CD54(ICAM-1))

  • 货号:RB9THY321026
  • 价格:面议
  • 点击:677
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产品介绍

产品参数

形态Liquid
宿主种属Mouse
克隆性Monoclonal
抗体亚型IgG2a-nd
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
浓度1mg/ml
内毒素水平Please contact the lab for this information.
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
种属反应性Human
靶标ICAM1, Major group rhinovirus receptor, CD54, ICAM-1, Intercellular adhesion molecule 1
储存缓冲液0.01M PBS, pH 7.4.
稳定性和储存Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
表达系统Mammalian Cells
登录号P05362
背景信息Bersanlimab (BI-505) is a fully human monoclonal antibody that targets intercellular adhesion molecule-1 (ICAM-1 or CD54). Bersanlimab has anticancer effects.
• Intercellular adhesion molecule-1 (ICAM-1): From molecular functions to clinical applications in cancer investigation., PMID:39317271
• Quercetin inhibits TNF-α induced HUVECs apoptosis and inflammation via downregulating NF-kB and AP-1 signaling pathway in vitro., PMID:32957369
• ICAM1 initiates CTC cluster formation and trans-endothelial migration in lung metastasis of breast cancer., PMID:34381029
• The Roles of Lipoprotein in Psoriasis., PMID:32013194
• Islet beta-cells and intercellular adhesion molecule-1 (ICAM-1): Integrating immune responses that influence autoimmunity and graft rejection., PMID:37619906
• Genetic Variation in Intercellular Adhesion Molecule-1 (ICAM-1) and Diastolic Heart Failure in the Black Population in the United States., PMID:37062471
• Systematic pan-cancer analysis insights into ICAM1 as an immunological and prognostic biomarker., PMID:38979944
Fusobacterium nucleatum promotes colorectal cancer cells adhesion to endothelial cells and facilitates extravasation and metastasis by inducing ALPK1/NF-κB/ICAM1 axis., PMID:35220887
• Gene regulation of intracellular adhesion molecule-1 (ICAM-1): A molecule with multiple functions., PMID:34715236
• Intercellular adhesion molecule-1 suppresses TMZ chemosensitivity in acquired TMZ-resistant gliomas by increasing assembly of ABCB1 on the membrane., PMID:38924997
别名BI-RR-1, BIRR-1, 142864-19-5
备注For research use only. Not suitable for clinical or therapeutic use.
【仅供科学研究使用】

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