| 形态 | Liquid |
|---|---|
| 宿主种属 | Humanized |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG1-kappa |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 1mg/ml |
| 内毒素水平 | Please contact the lab for this information. |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 靶标 | Activated leukocyte cell adhesion molecule, MEMD, CD166 antigen, ALCAM, CD166 |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 表达系统 | Mammalian Cells |
| 登录号 | Q13740 |
| 背景信息 | Praluzatamab is a monoclonal antibody targeting the activated leukocyte cell adhesion molecule (ALCAM/CD116). Praluzatamab can be used to synthesize Praluzatamab ravtansine (antibody-drug conjugates). Praluzatamab can be used for research of cancers. • Activated leukocyte cell adhesion molecule (ALCAM/CD166/MEMD), a novel actor in invasive growth, controls matrix metalloproteinase activity., PMID:16204050 • Prognostic significance of ALCAM (CD166/MEMD) expression in cutaneous melanoma patients., PMID:26134500 • Predictive impact of activated leukocyte cell adhesion molecule (ALCAM/CD166) in breast cancer., PMID:18172759 • Functional polymorphisms in CD166/ALCAM gene associated with increased risk for breast cancer in a Chinese population., PMID:21293922 • Identification of clinically significant tumor antigens by selecting phage antibody library on tumor cells in situ using laser capture microdissection., PMID:16982673 |
| 别名 | CX-2009, 2145109-70-0 |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |