当前位置:首页>产品中心>单抗/多抗>Anti-Human TRANCE/TNFSCoagulation Factor XI/RANK L Reference Antibody|抗人TRANCE/TNFSCoagulation Factor XI/RANK L参考抗体(靶标:人RANKL)

Anti-Human TRANCE/TNFSCoagulation Factor XI/RANK L Reference Antibody|抗人TRANCE/TNFSCoagulation Factor XI/RANK L参考抗体(靶标:人RANKL)

  • 货号:RB9THT439026
  • 价格:面议
  • 点击:214

产品介绍

产品参数

形态Liquid
宿主种属Human
克隆性Monoclonal
抗体亚型IgG4-kappa
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
浓度1mg/ml
内毒素水平Please contact the lab for this information.
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
种属反应性Human
靶标ODF, TNF-related activation-induced cytokine, Osteoclast differentiation factor, TNFSF11, TRANCE, Osteoprotegerin ligand, RANKL, Tumor necrosis factor ligand superfamily member 11, Receptor activator
储存缓冲液0.01M PBS, pH 7.4.
稳定性和储存Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
表达系统Mammalian Cells
登录号O14788
背景信息Narlumosbart (JMT103) is an IgG4κ antibody targeting receptor activator of nuclear factor-κB ligand (RANKL).
• Biology of the TRANCE axis., PMID:12787563
• Regulation of the differentiation and function of osteoclasts., PMID:10951393
• The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption., PMID:10646108
• Minireview: the OPG/RANKL/RANK system., PMID:11713196
• Importance of membrane- or matrix-associated forms of M-CSF and RANKL/ODF in osteoclastogenesis supported by SaOS-4/3 cells expressing recombinant PTH/PTHrP receptors., PMID:10976996
• Expression of parathyroid hormone-related protein (PTHrP), osteoclast differentiation factor (ODF)/receptor activator of nuclear factor-kappaB ligand (RANKL) and osteoclastogenesis inhibitory factor (OCIF)/osteoprotegerin (OPG) in ameloblastomas., PMID:14675140
• The molecular basis of osteoclast differentiation and activation., PMID:11277084
• The role of TNF-receptor family members and other TRAF-dependent receptors in bone resorption., PMID:11178122
• Characterization of osteoclast precursors in human blood., PMID:11122091
• Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction., PMID:10637272
别名2646587-68-8
备注For research use only. Not suitable for clinical or therapeutic use.
【仅供科学研究使用】

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