| 形态 | Liquid |
|---|---|
| 宿主种属 | Human |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG4-kappa |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 1mg/ml |
| 内毒素水平 | Please contact the lab for this information. |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 靶标 | ODF, TNF-related activation-induced cytokine, Osteoclast differentiation factor, TNFSF11, TRANCE, Osteoprotegerin ligand, RANKL, Tumor necrosis factor ligand superfamily member 11, Receptor activator |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 表达系统 | Mammalian Cells |
| 登录号 | O14788 |
| 背景信息 | Narlumosbart (JMT103) is an IgG4κ antibody targeting receptor activator of nuclear factor-κB ligand (RANKL). • Biology of the TRANCE axis., PMID:12787563 • Regulation of the differentiation and function of osteoclasts., PMID:10951393 • The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption., PMID:10646108 • Minireview: the OPG/RANKL/RANK system., PMID:11713196 • Importance of membrane- or matrix-associated forms of M-CSF and RANKL/ODF in osteoclastogenesis supported by SaOS-4/3 cells expressing recombinant PTH/PTHrP receptors., PMID:10976996 • Expression of parathyroid hormone-related protein (PTHrP), osteoclast differentiation factor (ODF)/receptor activator of nuclear factor-kappaB ligand (RANKL) and osteoclastogenesis inhibitory factor (OCIF)/osteoprotegerin (OPG) in ameloblastomas., PMID:14675140 • The molecular basis of osteoclast differentiation and activation., PMID:11277084 • The role of TNF-receptor family members and other TRAF-dependent receptors in bone resorption., PMID:11178122 • Characterization of osteoclast precursors in human blood., PMID:11122091 • Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction., PMID:10637272 |
| 别名 | 2646587-68-8 |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
| 产品名称 | 点击数 |
|---|---|
| 新冠病毒S蛋白中和抗体ELISA半定量检测试剂盒 | 7584 |
| 新冠病毒(Delta)S蛋白中和抗体ELISA检测试剂盒 | 7006 |
| 新冠病毒(奥密克戎)S蛋白中和抗体ELISA检测试剂盒 | 7432 |
| 人抗新冠病毒S蛋白IgG抗体ELISA检测试剂盒 | 7350 |
| 人抗新冠病毒S蛋白IgM亚型抗体ELISA检测试剂盒 | 7107 |
| 人抗新冠病毒N蛋白-IgG抗体ELISA检测试剂盒 | 7010 |
| 人抗新冠病毒奥密克戎RBD蛋白IgG亚型抗体ELISA检测试剂盒 | 7113 |
| 抗新冠病毒N蛋白-IgG抗体ELISA检测试剂盒 | 7006 |
| 碱性磷酸酶-抗体快速标记试剂盒 | 6732 |
| 即用型小鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装(6种) | 6843 |
| 鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装(6种) | 6922 |
| 鼠单抗Ig类/亚类鉴定用ELISA试剂盒(6种) | 7015 |
| 鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装(8种) | 6764 |
| 即用型小鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装(8种) | 7000 |
| 鼠单抗Ig类/亚类鉴定用ELISA试剂盒(8种) | 7099 |
| 单抗融合无忧套装 | 7214 |
| 即用型单抗细胞融合/亚克培养基 | 6880 |
| Frdbio®第三代抗体生物素标记试剂盒 | 7220 |
| 通用型抗体稀释液 | 6765 |
| HRP酶标抗体稀释液 | 7035 |