| 形态 | Liquid |
|---|---|
| 宿主种属 | Human |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG4-kappa |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 1mg/ml |
| 内毒素水平 | Please contact the lab for this information. |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 靶标 | ODF, TNF-related activation-induced cytokine, Osteoclast differentiation factor, TNFSF11, TRANCE, Osteoprotegerin ligand, RANKL, Tumor necrosis factor ligand superfamily member 11, Receptor activator |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 表达系统 | Mammalian Cells |
| 登录号 | O14788 |
| 背景信息 | Narlumosbart (JMT103) is an IgG4κ antibody targeting receptor activator of nuclear factor-κB ligand (RANKL). • Biology of the TRANCE axis., PMID:12787563 • Regulation of the differentiation and function of osteoclasts., PMID:10951393 • The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption., PMID:10646108 • Minireview: the OPG/RANKL/RANK system., PMID:11713196 • Importance of membrane- or matrix-associated forms of M-CSF and RANKL/ODF in osteoclastogenesis supported by SaOS-4/3 cells expressing recombinant PTH/PTHrP receptors., PMID:10976996 • Expression of parathyroid hormone-related protein (PTHrP), osteoclast differentiation factor (ODF)/receptor activator of nuclear factor-kappaB ligand (RANKL) and osteoclastogenesis inhibitory factor (OCIF)/osteoprotegerin (OPG) in ameloblastomas., PMID:14675140 • The molecular basis of osteoclast differentiation and activation., PMID:11277084 • The role of TNF-receptor family members and other TRAF-dependent receptors in bone resorption., PMID:11178122 • Characterization of osteoclast precursors in human blood., PMID:11122091 • Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction., PMID:10637272 |
| 别名 | 2646587-68-8 |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
| 产品名称 | 点击数 |
|---|---|
| 倍硫磷单抗 | 6338 |
| 多菌灵/阿苯达唑二合一单抗 | 6411 |
| 三氯噻嗪单抗 | 6510 |
| 吡唑醚菌酯单抗 | 6746 |
| 烯酰吗啉单抗 | 6583 |
| 抑霉唑单抗 | 6273 |
| 恶醚唑(苯醚甲环唑)单抗 | 6443 |
| 赛拉嗪(甲苯噻嗪)单抗 | 6470 |
| 辛硫磷单抗 | 6537 |
| 多效唑单抗 | 6426 |
| 对硫磷单抗 | 6621 |
| 丙溴磷单抗 | 6676 |
| 戊唑醇单抗 | 6673 |
| 莠去津单抗 | 6533 |
| 灭蝇胺单抗 | 6210 |
| 尼卡巴嗪代谢物(DNC)单抗 | 6490 |
| 2.4-二氯苯氧乙酸单抗 | 6337 |
| 甲基对硫磷单抗 | 6412 |
| 左旋咪唑单抗 | 6359 |
| 三唑磷单抗 | 6438 |