| 产品描述 | Iv0040 is a camelid-derived nanobody fused to a mouse IgG Fc fragment, designed to enhance stability and extend its in vivo half-life. It exhibits a high binding affinity to PD-L1, with a measured dissociation constant (KD) of 0.5 nM. Iv0040 can be effectively used for noninvasive imaging of PD-L1 expression in tumor-bearing mice through SPECT/CT, enabling real-time monitoring of PD-L1 distribution within the tumor microenvironment. |
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| 形态 | Liquid |
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| 宿主种属 | Mouse |
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| 克隆性 | Monoclonal |
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| 抗体亚型 | VHH-mFc |
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| 纯度 | >95% as determined by SDS-PAGE. |
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| 纯化方式 | Protein A/G purified from cell culture supernatant. |
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| 浓度 | 1 mg/ml |
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| 内毒素水平 | Please contact with the lab for this information. |
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| 应用 | ELISA, Neutralization |
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| 种属反应性 | Mouse |
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| 靶标 | Programmed cell death 1 ligand 1, PD-L1, PDCD1 ligand 1, Programmed death ligand 1, B7 homolog 1, B7-H1, CD274, Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1 |
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| 储存缓冲液 | 0.01M PBS, pH 7.4. |
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| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
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| 登录号 | Q9EP73 |
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| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
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