InVivoMAb anti-Human IFN-gamma Antibody|InVivoMAb抗人IFN-γ抗体(靶标：人干扰素γ)
- 货号：RB9THF813010
- 价格：面议
- 点击：329
产品介绍
产品参数
| 产品描述 | Iv0049 is a humanized monoclonal antibody that targets and neutralizes interferon-gamma (IFN-γ), a cytokine associated with inflammatory pathways. It has been investigated for potential use in autoimmune diseases such as Crohn’s disease. By binding IFN-γ, Iv0049 reduces downstream inflammatory signaling and its detrimental effects on intestinal barrier integrity. Early clinical studies have reported signs of therapeutic activity and generally manageable tolerability, although some serious adverse events, including disease exacerbation, were observed. Iv0049 has not been described as a currently marketed therapy, and its broader clinical development status remains unclear. |
|---|---|
| 形态 | Liquid |
| 宿主种属 | Human |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG1 |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 1 mg/ml |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, Neutralization, FCM |
| 种属反应性 | Human |
| 靶标 | Interferon gamma, IFN-gamma, Immune interferon, IFNG, IFN-γ |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 登录号 | P01579 |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
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