| 产品描述 | H27K15 is a monoclonal antibody targeting human CSF-1R. It partially inhibits CSF-1R signaling, prevents monocyte differentiation into M2-polarized macrophages, and promotes dendritic cell development. H27K15 has been tested in preclinical cancer models, showing potential to modulate the tumor microenvironment and reduce treatment-related rebound effects. |
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| 形态 | Liquid |
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| 宿主种属 | Human |
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| 克隆性 | Monoclonal |
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| 抗体亚型 | IgG1 |
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| 纯度 | >95% as determined by SDS-PAGE. |
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| 纯化方式 | Protein A/G purified from cell culture supernatant. |
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| 浓度 | 1 mg/ml |
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| 内毒素水平 | Please contact with the lab for this information. |
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| 应用 | ELISA, FCM, FuncS |
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| 种属反应性 | Human |
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| 靶标 | CD115, CSF-1 receptor, CSF1R, M-CSF-R, CSF-1-R, Proto-oncogene c-Fms, Macrophage colony-stimulating factor 1 receptor, CSF-1R, FMS |
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| 储存缓冲液 | 0.01M PBS, pH 7.4. |
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| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
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| 登录号 | P07333 |
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| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
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