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InVivoMAb Anti-Chikungunya Virus/CHIKV VLP Antibody|InVivoMAb抗基孔肯雅病毒/CHIKV VLP抗体(靶标:基孔肯雅病毒病毒样颗粒)

  • 货号:RB9TVK425010
  • 价格:面议
  • 点击:335

产品介绍

产品参数

产品描述m242 is a neutralizing monoclonal antibody against the Chikungunya virus E2 protein. As reported by Sun et al., eLife (2013), m242 binds the receptor-binding region of E2 and blocks viral attachment. The study demonstrates strong in vitro neutralization and indicates that m242 is suitable for use in in vivo CHIKV infection models.
形态Liquid
宿主种属Human
克隆性Monoclonal
抗体亚型IgG1
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
浓度1 mg/ml
内毒素水平Please contact with the lab for this information.
应用ELISA, Neutralization
种属反应性Chikungunya virus
靶标Structural polyprotein, p130, Capsid protein, 3.4.21.90, Coat protein, C, Precursor of protein E3/E2, p62, pE2, Assembly protein E3, Spike glycoprotein E2, E2 envelope glycoprotein, 6K protein, Spike
储存缓冲液0.01M PBS, pH 7.4.
稳定性和储存Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
登录号Q8JUX5, Q1H8W5, Q5XXP3
背景信息Chikungunya virus (CHIKV) virus-like particles (VLPs) are non-infectious, self-assembled structures composed of viral structural proteins, typically E1, E2, and capsid, that mimic the morphology and antigenicity of native virions without containing viral RNA. CHIKV VLPs are widely used in vaccine development, serological assay design, and immunological studies, as they safely elicit robust immune responses and enable the evaluation of neutralizing antibodies. Their structural similarity to live virus makes them valuable tools for both basic research and translational applications in CHIKV prevention and diagnosti
备注For research use only. Not suitable for clinical or therapeutic use.
【仅供科学研究使用】

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