当前位置：首页>产品中心>单抗/多抗>InVivoMAb Anti-Rat CD198/CCR8 Antibody|InVivoMAb抗大鼠CD198/CCR8抗体(靶标：大鼠CC趋化因子受体8/CD198)
InVivoMAb Anti-Rat CD198/CCR8 Antibody|InVivoMAb抗大鼠CD198/CCR8抗体(靶标：大鼠CC趋化因子受体8/CD198)
- 货号：RB9TRW444010
- 价格：面议
- 点击：463
产品介绍
产品参数
| 产品描述 | CCR8, a receptor selectively expressed on activated Tregs within tumors, plays a key role in maintaining local immunosuppression. Iv0256 is a rat-reactive CCR8 antibody with improved functional potency. In CD34 humanized mice, Iv0256 markedly reduced HCC827 lung tumor growth after intravenous administration. In syngeneic LLC and H22 models, intraperitoneal Iv0256 also achieved robust tumor suppression, displaying a pronounced dose-response pattern across tested doses. |
|---|---|
| 形态 | Liquid |
| 宿主种属 | Mouse |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG2a, kappa |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 1 mg/ml |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, Neutralization |
| 种属反应性 | Rat |
| 靶标 | C-C motif chemokine receptor 8, Ccr8 |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 登录号 | D4ADE0 |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
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