当前位置:首页>产品中心>单抗/多抗>Research Grade Liraglutide|研究级利拉鲁肽(靶标:利拉鲁肽(GLP-1受体激动剂))

Research Grade Liraglutide|研究级利拉鲁肽(靶标:利拉鲁肽(GLP-1受体激动剂))

  • 货号:RB9TSW328016
  • 价格:面议
  • 点击:560
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产品介绍

产品参数

形态Liquid
抗体亚型Biosynthetic GLP-1 analogs.
纯度>95% as determined by HPLC.
纯化方式Purified by HPLC.
浓度1 mg/ml
内毒素水平Please contact with the lab for this information.
应用ELISA, Functional assay, Research in vivo
种属反应性Human
靶标GLP-1 receptor, Glucagon-like peptide 1 receptor, GLP1R, GLP-1-R, GLP-1R
储存缓冲液0.01M PBS, pH 7.4.
稳定性和储存Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
登录号P43220
背景信息Liraglutide, 97% similar to native human GLP-1, differs primarily by substituting arginine for lysine at position 34 and involves attaching a C-16 fatty acid (palmitic acid) with a glutamic acid spacer at the remaining lysine residue at position 26.
• The physiology of glucagon-like peptide 1., PMID:17928588
• Glucagon-like peptide-1 receptor: mechanisms and advances in therapy., PMID:39289339
• The structure and function of the glucagon-like peptide-1 receptor and its ligands., PMID:21950636
• Structural basis for GLP-1 receptor activation by LY3502970, an orally active nonpeptide agonist., PMID:33177239
• Glucagon-like peptide-1 receptor., PMID:39626623
• Prognostic impact of glucagon-like peptide-1 receptor (GLP1R) expression on cancer survival and its implications for GLP-1R agonist therapy: an integrative analysis across multiple tumor types., PMID:39777709
• Safety issues with glucagon-like peptide-1 receptor agonists (pancreatitis, pancreatic cancer and cholelithiasis): Data from randomized controlled trials., PMID:28244632
• Glucagon-like-peptide 1 receptor agonism and attempted suicide: A Mendelian randomisation study to assess a potential causal association., PMID:38778795
• Glucagon-Like Peptide-1 Receptor Agonism and Suicide Risk: Evidence From Mendelian Randomization., PMID:38879463
• GLP-1, GIP/GLP-1, and GCGR/GLP-1 receptor agonists: Novel therapeutic agents for metabolic dysfunction-associated steatohepatitis., PMID:39735270
别名204656-20-2
种属Human
备注For research use only. Not suitable for clinical or therapeutic use.
【仅供科学研究使用】

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