当前位置:首页>产品中心>单抗/多抗>HEK293T Human CD20/MS4A1 Stable Cell Line|HEK293T人CD20/MS4A1稳定细胞系(靶标:人CD20/MS4A1稳定表达细胞系)

HEK293T Human CD20/MS4A1 Stable Cell Line|HEK293T人CD20/MS4A1稳定细胞系(靶标:人CD20/MS4A1稳定表达细胞系)

  • 货号:RB9THY257818
  • 价格:面议
  • 点击:400

产品介绍

产品参数

宿主种属HEK293T
应用FCM
靶标CD20/MS4A1
稳定性和储存Frozen in liquid nitrogen.
登录号P11836
背景信息

B-lymphocyte antigen CD20 (MS4A1) is a ~33 kDa protein. B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. CD20 is the therapeutic target of rituximab (MabThera) and obinutuzumab (Gazyva).

1. Li, H. et al. (2003) The Journal of biological chemistry 278, 42427-34. PMID: 12920111
2. Tedder, TF. et al. (1985) Journal of immunology (Baltimore, Md. : 1950) 135, 973-9. PMID: 3925015
3. Bubien, JK. et al. (1993) The Journal of cell biology 121, 1121-32. PMID: 7684739
4. Polyak, MJ. et al. (2008) The Journal of biological chemistry 283, 18545-52. PMID: 18474602
产品特性Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL)
种属Human
【仅供科学研究使用】

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