产品介绍
{, "description": "0", "form": "Liquid", "host_species": "Rabbit", "clonality": "Polyclonal", "isotype": "IgG", "purification": "Purified by antigen affinity column.", "endotoxin_level": "Please contact with the lab for this information.", "applications": "ELISA, IHC, WB", "species_reactivity": "Human", "target": "APOL, APOL1, Apo-L, ApoL, ApoL-I, Apolipoprotein L, Apolipoprotein L-I, Apolipoprotein L1", "immunogen": "E. coli - derived recombinant Human APOL1 (Thr227-Leu398).", "storage_buffer": "0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.", "product_usage_info": "ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000", "accession": "O14791", "background": "
Apolipoprotein L1 (APOL1) is a ~43 kDa protein. May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver. A component of trypanosome lytic factor of human serum; plays a crucial role in killing Trypanosoma brucei by forming pores in parasite lysosomal membranes and sensitizing T.brucei to oxidation-stimulated osmotic lysis.
2. Pérez-Morga, D. et al. (2005) Science (New York, N.Y.) 309, 469-72.
PMID: 160207353. Lecordier, L. et al. (2009) PLoS pathogens 5, e1000685.
PMID: 199974944. Greene, AS. et al. (2016) The Journal of biological chemistry 291, 3063-75.
PMID: 266456905. Tytler, EM. et al. (1995) Molecular and biochemical parasitology 69, 9-17.
PMID: 7723792", "note": "For research use only"}
【仅供科学研究使用】
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