| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | APOL, APOL1, Apo-L, ApoL, ApoL-I, Apolipoprotein L, Apolipoprotein L-I, Apolipoprotein L1 |
| 免疫原 | E. coli - derived recombinant Human APOL1 (Thr227-Leu398). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | O14791 |
| 背景信息 | Apolipoprotein L1 (APOL1) is a ~43 kDa protein. May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver. A component of trypanosome lytic factor of human serum; plays a crucial role in killing Trypanosoma brucei by forming pores in parasite lysosomal membranes and sensitizing T.brucei to oxidation-stimulated osmotic lysis. 1. Vanhamme, L. et al. (2003) Nature 422, 83-7. PMID: 12621437 2. Pérez-Morga, D. et al. (2005) Science (New York, N.Y.) 309, 469-72. PMID: 16020735 3. Lecordier, L. et al. (2009) PLoS pathogens 5, e1000685. PMID: 19997494 4. Greene, AS. et al. (2016) The Journal of biological chemistry 291, 3063-75. PMID: 26645690 5. Tytler, EM. et al. (1995) Molecular and biochemical parasitology 69, 9-17. PMID: 7723792 |
| 备注 | For research use only |