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Anti-Human APOL1 Polyclonal Antibody|抗人APOL1多克隆抗体(靶标:人载脂蛋白L1)

  • 货号:RB9THT291014
  • 价格:面议
  • 点击:241

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human
靶标APOL, APOL1, Apo-L, ApoL, ApoL-I, Apolipoprotein L, Apolipoprotein L-I, Apolipoprotein L1
免疫原E. coli - derived recombinant Human APOL1 (Thr227-Leu398).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号O14791
背景信息

Apolipoprotein L1 (APOL1) is a ~43 kDa protein. May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver. A component of trypanosome lytic factor of human serum; plays a crucial role in killing Trypanosoma brucei by forming pores in parasite lysosomal membranes and sensitizing T.brucei to oxidation-stimulated osmotic lysis.

1. Vanhamme, L. et al. (2003) Nature 422, 83-7. PMID: 12621437
2. Pérez-Morga, D. et al. (2005) Science (New York, N.Y.) 309, 469-72. PMID: 16020735
3. Lecordier, L. et al. (2009) PLoS pathogens 5, e1000685. PMID: 19997494
4. Greene, AS. et al. (2016) The Journal of biological chemistry 291, 3063-75. PMID: 26645690
5. Tytler, EM. et al. (1995) Molecular and biochemical parasitology 69, 9-17. PMID: 7723792
备注For research use only
【仅供科学研究使用】

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