当前位置：首页>产品中心>单抗/多抗>Anti-Clostridium perfringens Alpha-toxin/PLC Polyclonal Antibody|抗产气荚膜梭菌α毒素/PLC多克隆抗体(靶标：产气荚膜梭菌磷脂酶C/α毒素)
Anti-Clostridium perfringens Alpha-toxin/PLC Polyclonal Antibody|抗产气荚膜梭菌α毒素/PLC多克隆抗体(靶标：产气荚膜梭菌磷脂酶C/α毒素)
- 货号：RB9TJN878034
- 价格：面议
- 点击：526
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Clostridium perfringens |
| 靶标 | Alpha-toxin, EC:3.1.4.3, Hemolysin, Lecithinase, PLC, Phosphatidylcholine cholinephosphohydrolase, Phospholipase C, cpa, plc |
| 免疫原 | E. coli - derived recombinant Clostridium perfringens Alpha-toxin/PLC (Trp29-Lys398). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q9RF12 |
| 背景信息 | Phospholipase C (Alpha-toxin/PLC) is a ~45 kDa protein. Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Constitutes an essential virulence factor in gas gangrene. Binds to eukaryotic membranes where it hydrolyzes both phosphatidylcholine and sphingomyelin, causing cell rupture. The diacylglycerol produced can activate both the arachidonic acid pathway, leading to modulation of the inflammatory response cascade and thrombosis, and protein kinase C, leading to activation of eukaryotic phospholipases and further membrane damage. |
| 备注 | For research use only |
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