| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Hepatitis B virus genotype C, Hepatitis B virus genotype A1 subtype adw, Hepatitis B virus genotype C subtype ar, Hepatitis B virus genotype C subtype adr, Hepatitis B virus genotype C subtype ayr, He |
| 靶标 | L glycoprotein, L-HBsAg, LHB, Large S protein, Large envelope protein, Large surface protein, Major surface antigen, S |
| 免疫原 | E. coli - derived recombinant HBV HBsAg (Met1-Ile242). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P03140 |
| 背景信息 | Large envelope protein (HBsAg) is a ~43 kDa protein. The large envelope protein exists in two topological conformations, one which is termed 'external' or Le-HBsAg and the other 'internal' or Li-HBsAg. In its external conformation the protein attaches the virus to cell receptors and thereby initiating infection. This interaction determines the species specificity and liver tropism. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis. The large envelope protein also assures fusion between virion membrane and endosomal membrane. |
| 备注 | For research use only |