| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Human |
| 靶标 | FMN2, Formin-2 |
| 免疫原 | E. coli - derived recombinant Human FMN2 (Ser1361-Thr1722). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q9NZ56 |
| 背景信息 | Formin-2 (FMN2) is a ~180 kDa protein. Actin-binding protein that is involved in actin cytoskeleton assembly and reorganization. Acts as an actin nucleation factor and promotes assembly of actin filaments together with SPIRE1 and SPIRE2. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning, asymmetric oocyte division and polar body extrusion during female germ cell meiosis. Plays a role in responses to DNA damage, cellular stress and hypoxia by protecting CDKN1A against degradation, and thereby plays a role in stress-induced cell cycle arrest. 1. Vizcarra, CL. et al. (2011) Proceedings of the National Academy of Sciences of the United States of America 108, 11884-9. PMID: 21730168 2. Peng, KW. et al. (2012) Biochimica et biophysica acta 1820, 469-81. PMID: 22330775 3. Yamada, K. et al. (2013) Molecular cell 49, 922-33. PMID: 23375502 4. Belin, BJ. et al. (2015) eLife 4, e07735. PMID: 26287480 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
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| A族链球菌单克隆抗体 | 7510 |
| 甲型副伤寒沙门氏菌单抗 | 7288 |
| 麻疹病毒单克隆抗体 | 7520 |
| HBeAg单克隆抗体 | 7499 |
| 新型冠状病毒(SARS-COV-2)NP蛋白单克隆抗体 | 7000 |
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| 大肠杆菌单克隆抗体 | 7600 |
| LP-PLA2单克隆抗体 | 7568 |
| NT-PROBNP单克隆抗体 | 7313 |
| 半乳糖凝集素3单克隆抗体 | 7289 |
| D二聚体单克隆抗体 | 7311 |
| 肌钙蛋白单克隆抗体 | 7600 |
| 肌红蛋白单克隆抗体 | 7479 |
| AAT单克隆抗体 | 7270 |
| 人SAA单克隆抗体 | 7245 |
| 黏病毒抗性蛋白A单克隆抗体 | 7470 |
| 降钙素原单克隆抗体 | 7183 |