| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Rat, Mouse |
| 靶标 | MAPT, MAPTL, MTBT1, Microtubule-associated protein tau, Neurofibrillary tangle protein, PHF-tau, Paired helical filament-tau, TAU |
| 免疫原 | E. coli - derived recombinant Human MAPT/Tau/PHF-tau (Gln561-Glu689). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P10636 |
| 背景信息 | Microtubule-associated protein tau (MAPT/PHF-tau) is a ~78 kDa protein. Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. 1. Yoshida, H. et al. (2012) Journal of neurochemistry 120, 165-76. PMID: 21985311 2. Sandberg, A. et al. (2020) Neurobiology of disease 146, 105079. PMID: 32961270 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 炔诺酮单抗 | 5803 |
| 磺胺氯吡嗪单抗 | 5776 |
| 呋喃苯烯酸钠单抗 | 5606 |
| 呋喃它酮代谢物(2-NPAMOZ)单抗 | 5602 |
| 呋喃西林代谢物(2-NPSEM)单抗 | 5435 |
| 磺胺喹恶啉单抗 | 5674 |
| 苯丙酸诺龙单抗 | 5587 |
| 司帕沙星单抗 | 5458 |
| 妥布霉素单抗 | 5620 |
| 甲氧氯普胺单抗 | 5493 |
| 莫能菌素单抗 | 5613 |
| 多粘菌素B(粘菌素)单抗 | 5923 |
| 磺胺类单抗 | 5833 |
| 托灭酸(托芬那酸)单抗 | 5511 |
| 卡洛芬单抗 | 5437 |
| 喹乙醇代谢物MQCA单抗 | 5611 |
| 氟尼辛单抗 | 5569 |
| 磺胺二甲嘧啶(SM2)单抗 | 5362 |
| 诺龙(19-去甲睾酮)单抗 | 5447 |
| 阿苯达唑-2-氨基砜单抗 | 5418 |