| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Rat, Mouse |
| 靶标 | MAPT, MAPTL, MTBT1, Microtubule-associated protein tau, Neurofibrillary tangle protein, PHF-tau, Paired helical filament-tau, TAU |
| 免疫原 | E. coli - derived recombinant Human MAPT/Tau/PHF-tau (Gln561-Glu689). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P10636 |
| 背景信息 | Microtubule-associated protein tau (MAPT/PHF-tau) is a ~78 kDa protein. Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. 1. Yoshida, H. et al. (2012) Journal of neurochemistry 120, 165-76. PMID: 21985311 2. Sandberg, A. et al. (2020) Neurobiology of disease 146, 105079. PMID: 32961270 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 阿苯达唑砜单抗 | 5593 |
| 金刚烷胺单抗 | 5660 |
| 卡那霉素单抗 | 5790 |
| 黄曲霉毒素M1(AFM1)单抗 | 5754 |
| 群勃龙(孕三烯酮)(去甲雄三烯醇酮)单抗 | 6048 |
| 帕托珠利(妥曲珠利砜)单抗 | 5659 |
| 泰乐菌素单抗 | 5740 |
| 替米考星单抗 | 5815 |
| 新霉素单抗 | 5801 |
| 安普霉素单抗 | 5767 |
| 三聚氰胺(MEL)单抗 | 5663 |
| 双氟沙星单抗 | 5623 |
| 西地那非单抗 | 5710 |
| 阿苯达唑单抗 | 5515 |
| 醋酸甲羟孕酮(醋酸甲孕酮)单抗 | 5707 |
| 氟苯尼考单抗 | 5723 |
| 诺龙单抗 | 5821 |
| 达氟沙星单抗 | 5921 |
| 培氟沙星单抗 | 5785 |
| 庆大霉素单抗 | 5910 |