| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Rat, Mouse |
| 靶标 | MAPT, MAPTL, MTBT1, Microtubule-associated protein tau, Neurofibrillary tangle protein, PHF-tau, Paired helical filament-tau, TAU |
| 免疫原 | E. coli - derived recombinant Human MAPT/Tau/PHF-tau (Gln561-Glu689). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P10636 |
| 背景信息 | Microtubule-associated protein tau (MAPT/PHF-tau) is a ~78 kDa protein. Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. 1. Yoshida, H. et al. (2012) Journal of neurochemistry 120, 165-76. PMID: 21985311 2. Sandberg, A. et al. (2020) Neurobiology of disease 146, 105079. PMID: 32961270 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 氯丙嗪单抗 | 5801 |
| 西马特罗单抗 | 5786 |
| 孕酮单抗 | 5963 |
| 氯霉素(CAP)单抗 | 5897 |
| 红霉素单抗 | 5911 |
| 地克珠利单抗 | 5662 |
| 无色孔雀石绿(LMG)单抗 | 5878 |
| 雌二醇单抗 | 5527 |
| 孔雀石绿(MG)单抗 | 6044 |
| 双酚A单抗 | 5829 |
| 呋喃妥因代谢物(2-NPAHD)单抗 | 5681 |
| 己烯雌酚单抗 | 5719 |
| 莱克多巴胺(RAC)单抗 | 5857 |
| 林可霉素单抗 | 6174 |
| 抗青霉素受体单抗 | 5666 |
| 大观霉素单抗 | 5745 |
| 克伦特罗(CL)单抗 | 5973 |
| 沙拉沙星单抗(2H4) | 5792 |
| 磺胺对甲氧嘧啶(SMD)单抗 | 5941 |
| 磺胺类SAS单抗 | 5865 |