| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Rat, Mouse |
| 靶标 | MAPT, MAPTL, MTBT1, Microtubule-associated protein tau, Neurofibrillary tangle protein, PHF-tau, Paired helical filament-tau, TAU |
| 免疫原 | E. coli - derived recombinant Human MAPT/Tau/PHF-tau (Gln561-Glu689). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P10636 |
| 背景信息 | Microtubule-associated protein tau (MAPT/PHF-tau) is a ~78 kDa protein. Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. 1. Yoshida, H. et al. (2012) Journal of neurochemistry 120, 165-76. PMID: 21985311 2. Sandberg, A. et al. (2020) Neurobiology of disease 146, 105079. PMID: 32961270 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 心型脂肪酸结合蛋白鼠单抗 | 7883 |
| D-二聚体 G1 鼠单抗 | 7873 |
| D-二聚体 G2 鼠单抗 | 8226 |
| D-二聚体 G 鼠单抗 | 7816 |
| 抗人降钙素原鼠单抗 | 7970 |
| 抗人CRP鼠单抗 | 7897 |
| 抗人CRP鼠单抗-HRP | 7567 |
| 抗人SAA IgG鼠单抗 | 8010 |
| 抗生物素单抗 | 7835 |
| α-hcg单抗 | 7477 |
| β-hcg单抗 | 7766 |
| HIV配对鼠单抗 | 7887 |
| 脂蛋白小a鼠单抗 | 7729 |
| 红斑狼疮补体鼠单抗 | 7716 |
| 维生素D VDS鼠单抗 | 7800 |
| 二十五羟基维生素D3鼠单抗 | 7992 |
| 羊抗鼠抗体(定性) | 7665 |
| 羊抗鼠抗体(定量) | 7881 |
| RBC鼠单抗 | 7825 |
| HRP羊抗人抗体(精品) | 7898 |