| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Rat, Mouse |
| 靶标 | MAPT, MAPTL, MTBT1, Microtubule-associated protein tau, Neurofibrillary tangle protein, PHF-tau, Paired helical filament-tau, TAU |
| 免疫原 | E. coli - derived recombinant Human MAPT/Tau/PHF-tau (Gln561-Glu689). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P10636 |
| 背景信息 | Microtubule-associated protein tau (MAPT/PHF-tau) is a ~78 kDa protein. Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. 1. Yoshida, H. et al. (2012) Journal of neurochemistry 120, 165-76. PMID: 21985311 2. Sandberg, A. et al. (2020) Neurobiology of disease 146, 105079. PMID: 32961270 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 羊抗鸡IgY抗体(精品) | 8041 |
| 鼠抗人IgG(单抗) | 7539 |
| 鼠抗人IgM(单抗) | 7926 |
| 新冠病毒N单抗IgG人源化质控品 | 8279 |
| 新冠病毒N单抗IgM人源化质控品 | 7930 |
| 三聚氰胺单抗 | 7599 |
| 纳他霉素单抗 | 8056 |
| 孔雀石绿单抗 | 7817 |
| 隐性孔雀石绿单抗 | 7898 |
| 微囊藻毒素LR单抗 | 7671 |
| 黄曲霉毒素B1单抗 | 7554 |
| 黄曲霉毒素M1单抗 | 6955 |
| T2毒素单抗 | 7446 |
| 赭曲霉毒素单抗 | 7257 |
| 呕吐毒素单抗 | 7332 |
| 伏马毒素单抗 | 7663 |
| 黄曲霉总量单抗B1 | 6906 |
| 黄曲霉总量单抗B2 | 7493 |
| 黄曲霉总量单抗G1 | 7115 |
| 黄曲霉总量单抗G2 | 6994 |