| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | 250 kDa centrosomal protein, C-Nap1, CEP2, CEP250, CNAP1, Centrosomal Nek2-associated protein 1, Centrosomal protein 2, Centrosome-associated protein CEP250, Cep250 |
| 免疫原 | E. coli - derived recombinant Human CEP250 (Arg40-Thr293). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q9BV73 |
| 背景信息 | Centrosome-associated protein CEP250 is a ~281 kDa protein. Plays an important role in centrosome cohesion during interphase. Recruits CCDC102B to the proximal ends of centrioles. Maintains centrosome cohesion by forming intercentriolar linkages. Accumulates at the proximal end of each centriole, forming supramolecular assemblies with viscous material properties that promote organelle cohesion. May be involved in ciliogenesis. 1. Xia, Y. et al. (2018) Journal of cell science 131. PMID: 30404835 2. Mahen, R. (2022) PLoS biology 20, e3001854. PMID: 36282799 3. de Castro-Miró, M. et al. (2016) PloS one 11, e0168966. PMID: 28005958 |
| 备注 | For research use only |