| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Homo sapiens (Human) |
| 靶标 | Epididymis tissue protein Li 185a, NMB-R, NMBR, Neuromedin-B receptor, Neuromedin-B-preferring bombesin receptor |
| 免疫原 | E. coli - derived recombinant Human NMBR (Pro2-Val41&Asp100-Lys117&Glu178-Ile211&Ser328-Leu390). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P28336 |
| 背景信息 | Neuromedin-B receptor (NMBR) is a ~43 kDa protein. Receptor for neuromedin-B. Contributes to the maintenance of basal sigh rate through signaling in the pre-Botzinger complex, a cluster of several thousand neurons in the ventrolateral medulla responsible for inspiration during respiratory activity. Contributes to the induction of sneezing following exposure to chemical irritants or allergens which causes release of NMB by nasal sensory neurons and activation of NMBR-expressing neurons in the sneeze-evoking region of the brainstem. These in turn activate neurons of the caudal ventral respiratory group, giving rise to the sneezing response. Contributes to induction of acute itch, possibly through its activation on dorsal root ganglion neurons by the NMB peptide. 1. Corjay, MH. et al. (1991) The Journal of biological chemistry 266, 18771-9. PMID: 1655761 2. Yang, G. et al. (2019) Veterinary research 50, 80. PMID: 31601264 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 阿苯达唑砜单抗 | 5496 |
| 金刚烷胺单抗 | 5530 |
| 卡那霉素单抗 | 5701 |
| 黄曲霉毒素M1(AFM1)单抗 | 5673 |
| 群勃龙(孕三烯酮)(去甲雄三烯醇酮)单抗 | 5824 |
| 帕托珠利(妥曲珠利砜)单抗 | 5583 |
| 泰乐菌素单抗 | 5620 |
| 替米考星单抗 | 5717 |
| 新霉素单抗 | 5721 |
| 安普霉素单抗 | 5657 |
| 三聚氰胺(MEL)单抗 | 5577 |
| 双氟沙星单抗 | 5492 |
| 西地那非单抗 | 5643 |
| 阿苯达唑单抗 | 5438 |
| 醋酸甲羟孕酮(醋酸甲孕酮)单抗 | 5600 |
| 氟苯尼考单抗 | 5630 |
| 诺龙单抗 | 5712 |
| 达氟沙星单抗 | 5821 |
| 培氟沙星单抗 | 5688 |
| 庆大霉素单抗 | 5836 |