| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Homo sapiens (Human) |
| 靶标 | Epididymis tissue protein Li 185a, NMB-R, NMBR, Neuromedin-B receptor, Neuromedin-B-preferring bombesin receptor |
| 免疫原 | E. coli - derived recombinant Human NMBR (Pro2-Val41&Asp100-Lys117&Glu178-Ile211&Ser328-Leu390). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P28336 |
| 背景信息 | Neuromedin-B receptor (NMBR) is a ~43 kDa protein. Receptor for neuromedin-B. Contributes to the maintenance of basal sigh rate through signaling in the pre-Botzinger complex, a cluster of several thousand neurons in the ventrolateral medulla responsible for inspiration during respiratory activity. Contributes to the induction of sneezing following exposure to chemical irritants or allergens which causes release of NMB by nasal sensory neurons and activation of NMBR-expressing neurons in the sneeze-evoking region of the brainstem. These in turn activate neurons of the caudal ventral respiratory group, giving rise to the sneezing response. Contributes to induction of acute itch, possibly through its activation on dorsal root ganglion neurons by the NMB peptide. 1. Corjay, MH. et al. (1991) The Journal of biological chemistry 266, 18771-9. PMID: 1655761 2. Yang, G. et al. (2019) Veterinary research 50, 80. PMID: 31601264 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 氯丙嗪单抗 | 5679 |
| 西马特罗单抗 | 5647 |
| 孕酮单抗 | 5856 |
| 氯霉素(CAP)单抗 | 5783 |
| 红霉素单抗 | 5754 |
| 地克珠利单抗 | 5563 |
| 无色孔雀石绿(LMG)单抗 | 5785 |
| 雌二醇单抗 | 5416 |
| 孔雀石绿(MG)单抗 | 5951 |
| 双酚A单抗 | 5711 |
| 呋喃妥因代谢物(2-NPAHD)单抗 | 5597 |
| 己烯雌酚单抗 | 5585 |
| 莱克多巴胺(RAC)单抗 | 5754 |
| 林可霉素单抗 | 5903 |
| 抗青霉素受体单抗 | 5603 |
| 大观霉素单抗 | 5644 |
| 克伦特罗(CL)单抗 | 5860 |
| 沙拉沙星单抗(2H4) | 5684 |
| 磺胺对甲氧嘧啶(SMD)单抗 | 5853 |
| 磺胺类SAS单抗 | 5779 |