当前位置:首页>产品中心>单抗/多抗>Anti-Human KHDRBS3 Polyclonal Antibody|抗人KHDRBS3多克隆抗体(靶标:人KH RNA结合结构域含信号转导蛋白3)

Anti-Human KHDRBS3 Polyclonal Antibody|抗人KHDRBS3多克隆抗体(靶标:人KH RNA结合结构域含信号转导蛋白3)

  • 货号:RB9THD548014
  • 价格:面议
  • 点击:443

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Rat, Mouse, Human
靶标KH domain-containing, RNA-binding, signal transduction-associated protein 3, KHDRBS3, RNA-binding protein T-Star, SALP, SLM-2, SLM2, Sam68-like mammalian protein 2, Sam68-like phosphotyrosine protein
免疫原E. coli - derived recombinant Human KHDRBS3 (Asn51-Gly176).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号O75525
背景信息

KH domain-containing, RNA-binding, signal transduction-associated protein 3 (KHDRBS3) is a ~38 kDa protein. RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro. Binds optimally to RNA containing 5'-[AU]UAA-3' as a bipartite motif spaced by more than 15 nucleotides. Binds poly(A). RNA-binding abilities are down-regulated by tyrosine kinase PTK6.

1. Lee, J. et al. (1999) Gene 240, 133-47. PMID: 10564820
2. Ray, D. et al. (2009) Nature biotechnology 27, 667-70. PMID: 19561594
3. Feracci, M. et al. (2016) Nature communications 7, 10355. PMID: 26758068
4. Cohen, CD. et al. (2005) Journal of the American Society of Nephrology : JASN 16, 1958-65. PMID: 15901763
备注For research use only
【仅供科学研究使用】

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