| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Rat, Mouse, Human |
| 靶标 | EC:1.14.11.4, LH1, LLH, Lysyl hydroxylase 1, PLOD, PLOD1, Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 |
| 免疫原 | E. coli - derived recombinant Human PLOD1 (Gln636-Pro727). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q02809 |
| 背景信息 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (PLOD1) is a ~83 kDa protein. Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils. Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links (Probable). 1. Yeowell, HN. et al. (2000) Matrix biology : journal of the International Society for Matrix Biology 19, 37-46. PMID: 10686424 2. Walker, LC. et al. (2005) The Journal of investigative dermatology 124, 914-8. PMID: 15854030 3. Pirskanen, A. et al. (1996) The Journal of biological chemistry 271, 9398-402. PMID: 8621606 |
| 备注 | For research use only |