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Anti-Human PLOD1 Polyclonal Antibody|抗人PLOD1多克隆抗体(靶标:人前胶原赖氨酸-2-酮戊二酸-5-双加氧酶1)

  • 货号:RB9THX220014
  • 价格:面议
  • 点击:308

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Rat, Mouse, Human
靶标EC:1.14.11.4, LH1, LLH, Lysyl hydroxylase 1, PLOD, PLOD1, Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
免疫原E. coli - derived recombinant Human PLOD1 (Gln636-Pro727).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q02809
背景信息

Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (PLOD1) is a ~83 kDa protein. Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils. Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links (Probable).

1. Yeowell, HN. et al. (2000) Matrix biology : journal of the International Society for Matrix Biology 19, 37-46. PMID: 10686424
2. Walker, LC. et al. (2005) The Journal of investigative dermatology 124, 914-8. PMID: 15854030
3. Pirskanen, A. et al. (1996) The Journal of biological chemistry 271, 9398-402. PMID: 8621606
备注For research use only
【仅供科学研究使用】

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