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Anti-Human DNMBP Polyclonal Antibody|抗人DNMBP多克隆抗体(靶标:人动力蛋白结合蛋白)

  • 货号:RB9THD555014
  • 价格:面议
  • 点击:466

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human
靶标ARHGEF36, DNMBP, Dynamin-binding protein, KIAA1010, Scaffold protein Tuba, TUBA
免疫原E. coli - derived recombinant Human DNMBP (Met1-Leu202).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q6XZF7
背景信息

Dynamin-binding protein (DNMBP) is a ~177 kDa protein. Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions through F-actin organization in epithelial cells. Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation. Plays a role in ciliogenesis. May play a role in membrane trafficking between the cell surface and the Golgi.

1. Otani, T. et al. (2006) The Journal of cell biology 175, 135-46. PMID: 17015620
2. Rajabian, T. et al. (2009) Nature cell biology 11, 1212-8. PMID: 19767742
3. Qin, Y. et al. (2010) The Journal of cell biology 189, 661-9. PMID: 20479467
备注For research use only
【仅供科学研究使用】

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