| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | ARHGEF36, DNMBP, Dynamin-binding protein, KIAA1010, Scaffold protein Tuba, TUBA |
| 免疫原 | E. coli - derived recombinant Human DNMBP (Met1-Leu202). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q6XZF7 |
| 背景信息 | Dynamin-binding protein (DNMBP) is a ~177 kDa protein. Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions through F-actin organization in epithelial cells. Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation. Plays a role in ciliogenesis. May play a role in membrane trafficking between the cell surface and the Golgi. 1. Otani, T. et al. (2006) The Journal of cell biology 175, 135-46. PMID: 17015620 2. Rajabian, T. et al. (2009) Nature cell biology 11, 1212-8. PMID: 19767742 3. Qin, Y. et al. (2010) The Journal of cell biology 189, 661-9. PMID: 20479467 |
| 备注 | For research use only |