| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | Dimethylaniline monooxygenase [N-oxide-forming] 1, Dimethylaniline oxidase 1, EC:1.14.13.148, EC:1.14.13.8, FMO 1, FMO1, Fetal hepatic flavin-containing monooxygenase 1, Flavin-containing monooxygenas |
| 免疫原 | E. coli - derived recombinant Human FMO1 (Met1-Pro510). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q01740 |
| 背景信息 | Flavin-containing monooxygenase 1 (FMO1) is a ~60 kDa protein. Broad spectrum monooxygenase that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including xenobiotics. Catalyzes the S-oxygenation of hypotaurine to produce taurine, an organic osmolyte involved in cell volume regulation as well as a variety of cytoprotective and developmental processes. In vitro, catalyzes the N-oxygenation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. 1. Veeravalli, S. et al. (2020) Drug metabolism and disposition: the biological fate of chemicals 48, 378-385. PMID: 32156684 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 阿苯达唑砜单抗 | 5499 |
| 金刚烷胺单抗 | 5535 |
| 卡那霉素单抗 | 5702 |
| 黄曲霉毒素M1(AFM1)单抗 | 5675 |
| 群勃龙(孕三烯酮)(去甲雄三烯醇酮)单抗 | 5829 |
| 帕托珠利(妥曲珠利砜)单抗 | 5584 |
| 泰乐菌素单抗 | 5623 |
| 替米考星单抗 | 5722 |
| 新霉素单抗 | 5725 |
| 安普霉素单抗 | 5658 |
| 三聚氰胺(MEL)单抗 | 5578 |
| 双氟沙星单抗 | 5497 |
| 西地那非单抗 | 5645 |
| 阿苯达唑单抗 | 5440 |
| 醋酸甲羟孕酮(醋酸甲孕酮)单抗 | 5603 |
| 氟苯尼考单抗 | 5634 |
| 诺龙单抗 | 5712 |
| 达氟沙星单抗 | 5824 |
| 培氟沙星单抗 | 5689 |
| 庆大霉素单抗 | 5838 |