| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | Dimethylaniline monooxygenase [N-oxide-forming] 1, Dimethylaniline oxidase 1, EC:1.14.13.148, EC:1.14.13.8, FMO 1, FMO1, Fetal hepatic flavin-containing monooxygenase 1, Flavin-containing monooxygenas |
| 免疫原 | E. coli - derived recombinant Human FMO1 (Met1-Pro510). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q01740 |
| 背景信息 | Flavin-containing monooxygenase 1 (FMO1) is a ~60 kDa protein. Broad spectrum monooxygenase that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including xenobiotics. Catalyzes the S-oxygenation of hypotaurine to produce taurine, an organic osmolyte involved in cell volume regulation as well as a variety of cytoprotective and developmental processes. In vitro, catalyzes the N-oxygenation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. 1. Veeravalli, S. et al. (2020) Drug metabolism and disposition: the biological fate of chemicals 48, 378-385. PMID: 32156684 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 氯丙嗪单抗 | 5701 |
| 西马特罗单抗 | 5675 |
| 孕酮单抗 | 5876 |
| 氯霉素(CAP)单抗 | 5803 |
| 红霉素单抗 | 5773 |
| 地克珠利单抗 | 5582 |
| 无色孔雀石绿(LMG)单抗 | 5808 |
| 雌二醇单抗 | 5433 |
| 孔雀石绿(MG)单抗 | 5971 |
| 双酚A单抗 | 5739 |
| 呋喃妥因代谢物(2-NPAHD)单抗 | 5612 |
| 己烯雌酚单抗 | 5609 |
| 莱克多巴胺(RAC)单抗 | 5776 |
| 林可霉素单抗 | 5947 |
| 抗青霉素受体单抗 | 5611 |
| 大观霉素单抗 | 5669 |
| 克伦特罗(CL)单抗 | 5887 |
| 沙拉沙星单抗(2H4) | 5698 |
| 磺胺对甲氧嘧啶(SMD)单抗 | 5871 |
| 磺胺类SAS单抗 | 5808 |