| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Rat, Mouse |
| 靶标 | HPCN1, KCNA5, Potassium voltage-gated channel subfamily A member 5, Voltage-gated potassium channel HK2, Voltage-gated potassium channel subunit Kv1.5 |
| 免疫原 | E. coli - derived recombinant Human KCNA5 (Thr106-Gly247). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P22460 |
| 背景信息 | Potassium voltage-gated channel subfamily A member 5 (KCNA5) is a ~67 kDa protein. Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family members as well; channel properties depend on the type of alpha subunits that are part of the channel. Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and promote rapid inactivation. 1. Williams, CP. et al. (2002) The Journal of pharmacology and experimental therapeutics 302, 545-50. PMID: 12130714 2. Snyders, DJ. et al. (1993) The Journal of general physiology 101, 513-43. PMID: 8505626 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 阿苯达唑砜单抗 | 6181 |
| 金刚烷胺单抗 | 6348 |
| 卡那霉素单抗 | 6392 |
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| 群勃龙(孕三烯酮)(去甲雄三烯醇酮)单抗 | 7237 |
| 帕托珠利(妥曲珠利砜)单抗 | 6268 |
| 泰乐菌素单抗 | 6395 |
| 替米考星单抗 | 6318 |
| 新霉素单抗 | 6502 |
| 安普霉素单抗 | 6434 |
| 三聚氰胺(MEL)单抗 | 6352 |
| 双氟沙星单抗 | 6245 |
| 西地那非单抗 | 6327 |
| 阿苯达唑单抗 | 6191 |
| 醋酸甲羟孕酮(醋酸甲孕酮)单抗 | 6319 |
| 氟苯尼考单抗 | 6391 |
| 诺龙单抗 | 6420 |
| 达氟沙星单抗 | 6557 |
| 培氟沙星单抗 | 6384 |
| 庆大霉素单抗 | 6469 |