| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Rat, Mouse |
| 靶标 | HPCN1, KCNA5, Potassium voltage-gated channel subfamily A member 5, Voltage-gated potassium channel HK2, Voltage-gated potassium channel subunit Kv1.5 |
| 免疫原 | E. coli - derived recombinant Human KCNA5 (Thr106-Gly247). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P22460 |
| 背景信息 | Potassium voltage-gated channel subfamily A member 5 (KCNA5) is a ~67 kDa protein. Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family members as well; channel properties depend on the type of alpha subunits that are part of the channel. Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and promote rapid inactivation. 1. Williams, CP. et al. (2002) The Journal of pharmacology and experimental therapeutics 302, 545-50. PMID: 12130714 2. Snyders, DJ. et al. (1993) The Journal of general physiology 101, 513-43. PMID: 8505626 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 氯丙嗪单抗 | 6499 |
| 西马特罗单抗 | 6653 |
| 孕酮单抗 | 6674 |
| 氯霉素(CAP)单抗 | 6704 |
| 红霉素单抗 | 6669 |
| 地克珠利单抗 | 6204 |
| 无色孔雀石绿(LMG)单抗 | 6453 |
| 雌二醇单抗 | 6426 |
| 孔雀石绿(MG)单抗 | 6635 |
| 双酚A单抗 | 6523 |
| 呋喃妥因代谢物(2-NPAHD)单抗 | 6351 |
| 己烯雌酚单抗 | 6484 |
| 莱克多巴胺(RAC)单抗 | 6652 |
| 林可霉素单抗 | 7548 |
| 抗青霉素受体单抗 | 6257 |
| 大观霉素单抗 | 6420 |
| 克伦特罗(CL)单抗 | 6653 |
| 沙拉沙星单抗(2H4) | 6564 |
| 磺胺对甲氧嘧啶(SMD)单抗 | 6510 |
| 磺胺类SAS单抗 | 6504 |