当前位置:首页>产品中心>单抗/多抗>Anti-Human KCNIP4 Polyclonal Antibody|抗人KCNIP4多克隆抗体(靶标:人钾通道相互作用蛋白4/KChIP4)

Anti-Human KCNIP4 Polyclonal Antibody|抗人KCNIP4多克隆抗体(靶标:人钾通道相互作用蛋白4/KChIP4)

  • 货号:RB9THA290014
  • 价格:面议
  • 点击:215

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Rat, Mouse, Human
靶标A-type potassium channel modulatory protein 4, CALP, Calsenilin-like protein, KCHIP4, KCNIP4, KChIP4, Kv channel-interacting protein 4, Potassium channel-interacting protein 4
免疫原E. coli - derived recombinant Human KCNIP4 (Ser56-Ile250).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q6PIL6
背景信息

Kv channel-interacting protein 4 (KCNIP4) is a ~28 kDa protein. Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates KCND2 channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. Modulates KCND3/Kv4.3 currents. Isoform 4 does not increase KCND2 expression at the cell membrane. Isoform 4 retains KCND3 in the endoplasmic reticulum and negatively regulates its expression at the cell membrane.

1. Morohashi, Y. et al. (2002) The Journal of biological chemistry 277, 14965-75. PMID: 11847232
2. Jerng, HH. et al. (2008) The Journal of biological chemistry 283, 36046-59. PMID: 18957440
3. Tang, YQ. et al. (2013) The Journal of biological chemistry 288, 14727-41. PMID: 23576435
备注For research use only
【仅供科学研究使用】

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