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Anti-Human KCNIP4 Polyclonal Antibody|抗人KCNIP4多克隆抗体(靶标：人钾通道相互作用蛋白4/KChIP4)

形态	Liquid
宿主种属	Rabbit
克隆性	Polyclonal
抗体亚型	IgG
纯化方式	Purified by antigen affinity column.
内毒素水平	Please contact with the lab for this information.
应用	ELISA, IHC, WB
种属反应性	Rat, Mouse, Human
靶标	A-type potassium channel modulatory protein 4, CALP, Calsenilin-like protein, KCHIP4, KCNIP4, KChIP4, Kv channel-interacting protein 4, Potassium channel-interacting protein 4
免疫原	E. coli - derived recombinant Human KCNIP4 (Ser56-Ile250).
储存缓冲液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号	Q6PIL6
背景信息	Kv channel-interacting protein 4 (KCNIP4) is a ~28 kDa protein. Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates KCND2 channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. Modulates KCND3/Kv4.3 currents. Isoform 4 does not increase KCND2 expression at the cell membrane. Isoform 4 retains KCND3 in the endoplasmic reticulum and negatively regulates its expression at the cell membrane. 1. Morohashi, Y. et al. (2002) The Journal of biological chemistry 277, 14965-75. PMID: 11847232 2. Jerng, HH. et al. (2008) The Journal of biological chemistry 283, 36046-59. PMID: 18957440 3. Tang, YQ. et al. (2013) The Journal of biological chemistry 288, 14727-41. PMID: 23576435
备注	For research use only

【仅供科学研究使用】

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