Anti-Human MMP24 Polyclonal Antibody|抗人MMP24多克隆抗体(靶标：人基质金属蛋白酶24)
- 货号：RB9THV667024
- 价格：面议
- 点击：447
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Rat, Mouse, Human |
| 靶标 | EC:3.4.24.-, MMP-24, MMP24, MT-MMP 5, MT5-MMP, MT5MMP, MTMMP5, Matrix metalloproteinase-24, Membrane-type matrix metalloproteinase 5, Membrane-type-5 matrix metalloproteinase, Processed matrix metallo |
| 免疫原 | E. coli - derived recombinant Human MMP24 (Ile379-Trp566). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q9Y5R2 |
| 背景信息 | Matrix metalloproteinase-24 (MMP24) is a ~73 kDa protein. Metalloprotease that mediates cleavage of N-cadherin (CDH2) and acts as a regulator of neuro-immune interactions and neural stem cell quiescence. Involved in cell-cell interactions between nociceptive neurites and mast cells, possibly by mediating cleavage of CDH2, thereby acting as a mediator of peripheral thermal nociception and inflammatory hyperalgesia. Key regulator of neural stem cells quiescence by mediating cleavage of CDH2, affecting CDH2-mediated anchorage of neural stem cells to ependymocytes in the adult subependymal zone, leading to modulate their quiescence. May play a role in axonal growth. Able to activate progelatinase A. |
| 备注 | For research use only |
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