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Anti-Human CD166/ALCAM Polyclonal Antibody|抗人CD166/ALCAM多克隆抗体(靶标:人活化白细胞黏附分子/CD166)

  • 货号:RB9THC678014
  • 价格:面议
  • 点击:249

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human, Mouse, Rat
靶标ALCAM, Activated leukocyte cell adhesion molecule, CD166, CD166 antigen, MEMD
免疫原E. coli - derived recombinant Human CD166/ALCAM (Trp28-Lys527).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q13740
背景信息

CD166 antigen (ALCAM) is a ~65 kDa protein. Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts. Promotes T-cell activation and proliferation via its interactions with CD6. Contributes to the formation and maturation of the immunological synapse via its interactions with CD6. Mediates homotypic interactions with cells that express ALCAM. Acts as a ligand for the LILRB4 receptor, enhancing LILRB4-mediated inhibition of T cell proliferation.

1. Hassan, NJ. et al. (2004) European journal of immunology 34, 930-40. PMID: 15048703
2. Ikeda, K. et al. (2004) The Journal of biological chemistry 279, 55315-23. PMID: 15496415
3. Zimmerman, AW. et al. (2006) Blood 107, 3212-20. PMID: 16352806
4. Iolyeva, M. et al. (2013) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 27, 978-90. PMID: 23169771
5. Escoda-Ferran, C. et al. (2014) FEBS letters 588, 2805-13. PMID: 24945728
6. Bowen, MA. et al. (1995) The Journal of experimental medicine 181, 2213-20. PMID: 7760007
7. Gimferrer, I. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 2262-70. PMID: 15294938
8. Xu, Z. et al. (2018) Journal of immunology (Baltimore, Md. : 1950) 200, 1207-1219. PMID: 29263213
9. Chitteti, BR. et al. (2014) Blood 124, 519-29. PMID: 24740813
备注For research use only
【仅供科学研究使用】

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