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Anti-Mouse CTSG Polyclonal Antibody|抗小鼠CTSG多克隆抗体(靶标:小鼠组织蛋白酶G)

  • 货号:RB9TMY284014
  • 价格:面议
  • 点击:271

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Mouse
靶标Cathepsin G, Ctsg, EC:3.4.21.20, VSP, Vimentin-specific protease
免疫原E. coli - derived recombinant Mouse CTSG (Met35-Pro247).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号P28293
背景信息

Cathepsin G (CTSG) is a ~29 kDa protein. Serine protease with trypsin- and chymotrypsin-like specificity. Also displays antibacterial activity against Gram-negative and Gram-positive bacteria independent of its protease activity. Prefers Phe and Tyr residues in the P1 position of substrates but also cleaves efficiently after Trp and Leu. Shows a preference for negatively charged amino acids in the P2' position and for aliphatic amino acids both upstream and downstream of the cleavage site. Required for recruitment and activation of platelets which is mediated by the F2RL3/PAR4 platelet receptor.

1. Nakamura, N. et al. (1992) European journal of biochemistry 205, 947-54. PMID: 1577012
备注For research use only
【仅供科学研究使用】

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