| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse |
| 靶标 | B-cell stimulatory factor 1, BSF-1, Binetrakin, IL-4, IL4, Interleukin-4, Lymphocyte stimulatory factor 1, Pitrakinra |
| 免疫原 | E. coli - derived recombinant Mouse IL4 (His23-Ser140). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P07750 |
| 背景信息 | Interleukin-4 (IL4) is a ~15 kDa protein. Cytokine secreted primarily by mast cells, T-cells, eosinophils, and basophils that plays a role in regulating antibody production, hematopoiesis and inflammation, and the development of effector T-cell responses. Induces the expression of class II MHC molecules on resting B-cells. Enhances both secretion and cell surface expression of IgE and IgG1. Also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. 1. Lee, F. et al. (1986) Proceedings of the National Academy of Sciences of the United States of America 83, 2061-5. PMID: 3083412 2. Sideras, P. et al. (1987) Advances in experimental medicine and biology 213, 227-36. PMID: 3498301 3. Terawaki, S. et al. (2015) The Journal of cell biology 210, 1133-52. PMID: 26416964 4. Moon, ML. et al. (2015) Behavior genetics 45, 451-60. PMID: 25772794 5. Bogale, TMH. et al. (2017) Journal of immunology (Baltimore, Md. : 1950) 198, 2681-2688. PMID: 28202615 6. Edukulla, R. et al. (2015) The Journal of biological chemistry 290, 13510-20. PMID: 25847241 7. Kaplan, MH. et al. (1996) Immunity 4, 313-9. PMID: 8624821 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 阿苯达唑砜单抗 | 5927 |
| 金刚烷胺单抗 | 6084 |
| 卡那霉素单抗 | 6139 |
| 黄曲霉毒素M1(AFM1)单抗 | 6110 |
| 群勃龙(孕三烯酮)(去甲雄三烯醇酮)单抗 | 6693 |
| 帕托珠利(妥曲珠利砜)单抗 | 6017 |
| 泰乐菌素单抗 | 6096 |
| 替米考星单抗 | 6135 |
| 新霉素单抗 | 6201 |
| 安普霉素单抗 | 6168 |
| 三聚氰胺(MEL)单抗 | 6071 |
| 双氟沙星单抗 | 6002 |
| 西地那非单抗 | 6104 |
| 阿苯达唑单抗 | 5934 |
| 醋酸甲羟孕酮(醋酸甲孕酮)单抗 | 6096 |
| 氟苯尼考单抗 | 6155 |
| 诺龙单抗 | 6222 |
| 达氟沙星单抗 | 6305 |
| 培氟沙星单抗 | 6157 |
| 庆大霉素单抗 | 6274 |