| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse |
| 靶标 | B-cell stimulatory factor 1, BSF-1, Binetrakin, IL-4, IL4, Interleukin-4, Lymphocyte stimulatory factor 1, Pitrakinra |
| 免疫原 | E. coli - derived recombinant Mouse IL4 (His23-Ser140). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P07750 |
| 背景信息 | Interleukin-4 (IL4) is a ~15 kDa protein. Cytokine secreted primarily by mast cells, T-cells, eosinophils, and basophils that plays a role in regulating antibody production, hematopoiesis and inflammation, and the development of effector T-cell responses. Induces the expression of class II MHC molecules on resting B-cells. Enhances both secretion and cell surface expression of IgE and IgG1. Also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. 1. Lee, F. et al. (1986) Proceedings of the National Academy of Sciences of the United States of America 83, 2061-5. PMID: 3083412 2. Sideras, P. et al. (1987) Advances in experimental medicine and biology 213, 227-36. PMID: 3498301 3. Terawaki, S. et al. (2015) The Journal of cell biology 210, 1133-52. PMID: 26416964 4. Moon, ML. et al. (2015) Behavior genetics 45, 451-60. PMID: 25772794 5. Bogale, TMH. et al. (2017) Journal of immunology (Baltimore, Md. : 1950) 198, 2681-2688. PMID: 28202615 6. Edukulla, R. et al. (2015) The Journal of biological chemistry 290, 13510-20. PMID: 25847241 7. Kaplan, MH. et al. (1996) Immunity 4, 313-9. PMID: 8624821 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 氯丙嗪单抗 | 6199 |
| 西马特罗单抗 | 6253 |
| 孕酮单抗 | 6377 |
| 氯霉素(CAP)单抗 | 6360 |
| 红霉素单抗 | 6360 |
| 地克珠利单抗 | 5965 |
| 无色孔雀石绿(LMG)单抗 | 6197 |
| 雌二醇单抗 | 5996 |
| 孔雀石绿(MG)单抗 | 6399 |
| 双酚A单抗 | 6241 |
| 呋喃妥因代谢物(2-NPAHD)单抗 | 6057 |
| 己烯雌酚单抗 | 6175 |
| 莱克多巴胺(RAC)单抗 | 6316 |
| 林可霉素单抗 | 6927 |
| 抗青霉素受体单抗 | 6001 |
| 大观霉素单抗 | 6134 |
| 克伦特罗(CL)单抗 | 6377 |
| 沙拉沙星单抗(2H4) | 6205 |
| 磺胺对甲氧嘧啶(SMD)单抗 | 6302 |
| 磺胺类SAS单抗 | 6230 |