Anti-Mouse NUMB Polyclonal Antibody|抗小鼠NUMB多克隆抗体(靶标：小鼠Numb蛋白)
- 货号：RB9TMW709014
- 价格：面议
- 点击：278
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Rat, Mouse, Human |
| 靶标 | C14orf41, NUMB, Protein S171, Protein numb homolog, h-Numb |
| 免疫原 | E. coli - derived recombinant Mouse NUMB (Val16-Ala200). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q9QZS3 |
| 背景信息 | Protein numb homolog is a ~70 kDa protein. Regulates clathrin-mediated receptor endocytosis. Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. 1. Zhong, W. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 6844-9. PMID: 10841580 2. Petersen, PH. et al. (2002) Nature 419, 929-34. PMID: 12410312 3. Petersen, PH. et al. (2004) Nature neuroscience 7, 803-11. PMID: 15273690 4. Kuo, CT. et al. (2006) Cell 127, 1253-64. PMID: 17174898 |
| 备注 | For research use only |
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