Anti-Mouse NUMB Polyclonal Antibody|抗小鼠NUMB多克隆抗体(靶标：小鼠Numb蛋白)

形态	Liquid
宿主种属	Rabbit
克隆性	Polyclonal
抗体亚型	IgG
纯化方式	Purified by antigen affinity column.
内毒素水平	Please contact with the lab for this information.
应用	ELISA, IHC, WB
种属反应性	Rat, Mouse, Human
靶标	C14orf41, NUMB, Protein S171, Protein numb homolog, h-Numb
免疫原	E. coli - derived recombinant Mouse NUMB (Val16-Ala200).
储存缓冲液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号	Q9QZS3
背景信息	Protein numb homolog is a ~70 kDa protein. Regulates clathrin-mediated receptor endocytosis. Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. 1. Zhong, W. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 6844-9. PMID: 10841580 2. Petersen, PH. et al. (2002) Nature 419, 929-34. PMID: 12410312 3. Petersen, PH. et al. (2004) Nature neuroscience 7, 803-11. PMID: 15273690 4. Kuo, CT. et al. (2006) Cell 127, 1253-64. PMID: 17174898
备注	For research use only

【仅供科学研究使用】

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