| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Human |
| 靶标 | 140 kDa TATA box-binding protein-associated factor, TAF(II)140, TAF140, TAF3, TAFII-140, TAFII140, TBP-associated factor 3, Transcription initiation factor TFIID 140 kDa subunit, Transcription initiat |
| 免疫原 | E. coli - derived recombinant Human TAF3 (Cys2-Phe99). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q5VWG9 |
| 背景信息 | Transcription initiation factor TFIID subunit 3 (TAF3) is a ~103 kDa protein. The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. The TFIID complex structure can be divided into 3 modules TFIID-A, TFIID-B, and TFIID-C. TAF3 forms the TFIID-A module together with TAF5 and TBP. 1. Chen, X. et al. (2021) Science (New York, N.Y.) 372. PMID: 33795473 2. Gangloff, YG. et al. (2001) Molecular and cellular biology 21, 5109-21. PMID: 11438666 |
| 备注 | For research use only |