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Anti-Human TAF3 Polyclonal Antibody|抗人TAF3多克隆抗体(靶标:人TATA盒结合蛋白相关因子3)

  • 货号:RB9THD303014
  • 价格:面议
  • 点击:437

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Mouse, Human
靶标140 kDa TATA box-binding protein-associated factor, TAF(II)140, TAF140, TAF3, TAFII-140, TAFII140, TBP-associated factor 3, Transcription initiation factor TFIID 140 kDa subunit, Transcription initiat
免疫原E. coli - derived recombinant Human TAF3 (Cys2-Phe99).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q5VWG9
背景信息

Transcription initiation factor TFIID subunit 3 (TAF3) is a ~103 kDa protein. The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. The TFIID complex structure can be divided into 3 modules TFIID-A, TFIID-B, and TFIID-C. TAF3 forms the TFIID-A module together with TAF5 and TBP.

1. Chen, X. et al. (2021) Science (New York, N.Y.) 372. PMID: 33795473
2. Gangloff, YG. et al. (2001) Molecular and cellular biology 21, 5109-21. PMID: 11438666
备注For research use only
【仅供科学研究使用】

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