| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | FAST kinase domain-containing protein 3, mitochondrial, FASTKD3 |
| 免疫原 | E. coli - derived recombinant Human FASTKD3 (Val84-Tyr516). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q14CZ7 |
| 背景信息 | FAST kinase domain-containing protein 3, mitochondrial (FASTKD3) is a ~75 kDa protein. Required for normal mitochondrial respiration. Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND2, MT-ND3, MT-CYTB, MT-CO2, and MT-ATP8/6. Promotes MT-CO1 mRNA translation and increases mitochondrial complex IV assembly and activity. 1. Simarro, M. et al. (2010) Biochemical and biophysical research communications 401, 440-6. PMID: 20869947 2. Boehm, E. et al. (2016) The Journal of biological chemistry 291, 25877-25887. PMID: 27789713 |
| 备注 | For research use only |